Historical Review and Recent Advances - Chapter 11

نویسندگان

  • George F. Smith
  • Dharmapuri Vidyasagar
  • Phillip J. Goldstein
چکیده

The examination of birth asphyxia from a historical perspective presents several intriguing problems. First, of course, there is no satisfactory definition. Clinicians, biochemists and pathologists all seem to use the phrase, but a universal definition is lacking. Dr. Eastman of Hopkins called asphyxia "an infelicity of etymology" since the Greek derivation of asphyxia meant "without pulse." A second problem seems to be that, within each specialty studying asphyxia, once a definition is established, the exceptions are enormous. For instance, to the pathologist, a defined "asphyxic" lesion may occur without any clinical or biochemical history of asphyxia. The term asphyxia when defined in physiology textbooks includes hypoxia plus hypercarbia. Alternatively, biochemical evidence of asphyxia is present in tremendous numbers of children who, in fact, are clinically completely normal.

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تاریخ انتشار 2006